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galeterone  (Selleck Chemicals)


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    Selleck Chemicals galeterone
    Galeterone, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 90/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/galeterone/Galeterone/10__1002_slash_slct__202203393-99-8-11
    Average 90 stars, based on 4 article reviews
    galeterone - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Synthesized:

    Article Title: Design and Synthesis of New Agents for Prostate Cancer Treatment Inspired by Steroidal CYP17 A1 Inhibitors
    Article Snippet: Steroid derivatives modified with nitrogen containing heterocycles attract attention as anticancer agents for prostate cancer treatment.. In this study we have developed a simple and convenient procedure for preparation of 17(20)-21-norpregnene and androst-16-ene 2’-oxazolinyl and 2’-benzoxazolyl derivatives, based on the reaction of an appropriately modified steroidal carboxylic acid with 1,2-amino alcohols or o-aminophenol.. Using this method we conducted synthesis a series of new steroid hybrids differing either in the structure of steroidal part, or in the structure of nitrogen containing heterocycle (23 compounds in total).



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    Image Search Results


    Structures of abiraterone acetate ( 1 ), abiraterone ( 2 ), and galeterone ( 3 ).

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: Structures of abiraterone acetate ( 1 ), abiraterone ( 2 ), and galeterone ( 3 ).

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques:

    Number of published papers by year from PubMed (results obtained using the “All” search field and keywords “abiraterone” ( A ) and “galeterone” ( C )) and Scopus (results obtained using the “Article title, Abstract, Keywords” field and keywords “abiraterone” ( B ) and “galeterone” ( D )).

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: Number of published papers by year from PubMed (results obtained using the “All” search field and keywords “abiraterone” ( A ) and “galeterone” ( C )) and Scopus (results obtained using the “Article title, Abstract, Keywords” field and keywords “abiraterone” ( B ) and “galeterone” ( D )).

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques:

    Distribution of documents by type from Scopus (results obtained using keywords “abiraterone” or “galeterone” and the “Article title, Abstract, Keywords” field).

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: Distribution of documents by type from Scopus (results obtained using keywords “abiraterone” or “galeterone” and the “Article title, Abstract, Keywords” field).

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques:

    Distribution of documents by subject area from Scopus (results obtained using keywords “abiraterone” or “galeterone” and the “Article title, Abstract, Keywords” field).

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: Distribution of documents by subject area from Scopus (results obtained using keywords “abiraterone” or “galeterone” and the “Article title, Abstract, Keywords” field).

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques:

    VOSviewer generated an overlay visualization graph with the co-occurrence of keywords related to galeterone.

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: VOSviewer generated an overlay visualization graph with the co-occurrence of keywords related to galeterone.

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques: Generated

    Synthesis of galeterone ( 3 ) from dehydroepiandrosterone acetate ( 4 ). Reagents and conditions: (a) POCl 3 -DMF, CH 3 Cl, Ar, reflux; (b) benzimidazole, K 2 CO 3 , DMF, Ar, 80 °C; (c) 10% Pd on activated charcoal, PhCN, reflux; (d) 10% methanolic KOH, Ar, rt.

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: Synthesis of galeterone ( 3 ) from dehydroepiandrosterone acetate ( 4 ). Reagents and conditions: (a) POCl 3 -DMF, CH 3 Cl, Ar, reflux; (b) benzimidazole, K 2 CO 3 , DMF, Ar, 80 °C; (c) 10% Pd on activated charcoal, PhCN, reflux; (d) 10% methanolic KOH, Ar, rt.

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques: Reflux

    In vitro and in vivo metabolism of galeterone.

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: In vitro and in vivo metabolism of galeterone.

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques: In Vitro, In Vivo

    Galeterone derivatives 26 – 33 .

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: Galeterone derivatives 26 – 33 .

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques:

    C-3-modified derivatives of galeterone.

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: C-3-modified derivatives of galeterone.

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques: Modification

    Structures of galeterone analogs 40 – 46 .

    Journal: Pharmaceutics

    Article Title: Abiraterone and Galeterone, Powerful Tools Against Prostate Cancer: Present and Perspective

    doi: 10.3390/pharmaceutics16111401

    Figure Lengend Snippet: Structures of galeterone analogs 40 – 46 .

    Article Snippet: These data enabled galeterone to be licensed to Tokai Pharmaceuticals Inc., Cambridge, MA, for further preclinical and clinical studies and granted it a new code name, TOK-001 [ ].

    Techniques: